A brain-computer interface tested at a participant's home translated brain signals into speech, offering a new communication option for people with paralysis caused by ALS.
NIH-funded research suggests that moderate-to-vigorous physical activity and adequate sleep could lower inflammation and artery plaque buildup associated with some blood stem…
Research suggests that infants exposed to high metal levels, especially between 6 and 9 months old, may face increased risks of mental health symptoms and brain changes later in…
Wildfire smoke can affect health far beyond the fire zone, causing respiratory and cardiovascular problems, and researchers are working to better understand and mitigate these…
Grief varies widely among individuals and impacts both emotional and physical health. Researchers explore diverse ways to support those coping with loss.
Alcohol use during summer activities such as swimming, boating, and driving may significantly increase the risk of accidents and health problems, according to the NIAAA.
Research indicates that individuals diagnosed with melanoma at a young age or with multiple melanomas may be more likely to carry genetic mutations, supporting expanded genetic…
A study suggests that higher blood levels of Alzheimer’s-related proteins in people in their 50s and 60s may be linked to declines in processing speed and executive function.
The NIH Science Education Partnership Award (SEPA) program aims to support educational projects that increase biomedical research understanding and promote STEM careers among…
A collection of lesson plans, virtual labs, videos, and interactive experiences helps students understand genetics, genomics, and biomedical engineering concepts.
Researchers have identified elevated levels of certain circular RNAs in blood that may more accurately forecast the onset of Alzheimer’s symptoms compared to current biomarkers.
Data from over 747,000 participants makes the All of Us Research Program the largest combined genomics and electronic health records database globally, including new proteomics…
Noise-induced hearing loss can affect people of all ages due to exposure to loud sounds, either from a single intense noise or continuous loud environments. It is preventable but…
Researchers created an AI tool that designs improved antibacterial peptides, potentially accelerating the development of new antibiotics to combat resistant bacteria.
Researchers used video games to measure how people with depression assess rewards, finding differences in decisional reference points that may aid faster diagnosis.
NIH reports on stem cell studies improving understanding of blood formation and eye disease therapies, alongside the DASH diet's continued top ranking for cardiovascular health.
Victor Ambros, Gary Ruvkun, and David Baker, long-time NIGMS grantees, have received 2024 Nobel Prizes for their pioneering work in microRNA discovery and computational protein…
Several lesson plans and curricula are designed to teach students about the health impacts of climate change, including infectious diseases and environmental interactions.
This resource explains that a person's identity results from both inherited DNA and environmental influences, highlighting that genetic code is not the sole determinant.
The NIH provides various educational tools and materials including virtual reality experiences and hands-on biology modules for students from elementary to high school.
Several educational programs offer resources on sleep biology, genetics, immunology, neuroscience, cannabis effects, and hearing protection for students from elementary to high…
This resource explains the journey of smells to the brain, their importance in daily activities, and potential reasons for changes in the sense of smell.
The Division of Program Coordination, Planning, and Strategic Initiatives at NIH facilitates collaborative research across multiple institutes and coordinates efforts in areas…
The NIH Executive Secretariat supports the NIH Director and Principal Deputy Director by coordinating information flow, communications, and decision-making across NIH and with…
A long-term NIH-supported clinical trial found that lifestyle changes significantly reduced the risk of multimorbidity in adults with prediabetes compared to placebo, while…
The National Institutes of Health has created the Office of Research Innovation, Validation, and Application to advance human-relevant research methods and limit animal use.
Huntington’s disease, caused by a defective huntingtin gene, leads to progressive movement and cognitive impairments. Research seeks to address its genetic origins.
A consortium funded by NIH developed the first comprehensive atlas and classification of senescent cells, aimed at informing therapies for age-related diseases.
The NIH Loan Repayment Programs repay qualified educational debt to retain health professionals pursuing biomedical and biobehavioral research careers.
NIH scientists discovered that mutations in the GPR15 gene disrupt regulatory immune cells in the colon, offering new paths for IBD diagnosis and treatment.
Dr. Steven Schiff, a pediatric neurosurgeon and global health researcher, was named director of the Fogarty International Center and NIH associate director for international…
NIH-funded researchers developed an AI tool identifying tumor cellular neighborhoods linked to treatment response, potentially detectable via blood tests.
NIH will close on June 19 and July 3, 2026, highlights requirements for career development award recipients, and introduces new small business funding opportunities and guidance…
The NHLBI emphasizes that controlling asthma can enable a full and active life, promoting educational resources, community partnerships, and ongoing research.
The NIH has received FDA approval to begin a phase I clinical trial testing mitragynine for safety in humans as a potential treatment for opioid use disorder.
Recent NIH-sponsored clinical trials show promising results in malaria prevention, cancer therapies, cognitive decline reduction, and heart disease risk.
Anyone can contribute to medical research through citizen science projects like the All of Us Research Program, which seeks to build a diverse health database.
NIH researchers reveal how semaglutide influences intracellular signaling in brain neurons, highlighting cAMP's role and potential to enhance weight-loss treatments.
Researchers launched an online decision-support tool to help clinicians diagnose and treat pediatric amblyopia, expanding access amid a specialist shortage.
A study funded by NIH isolated and mapped the first detailed suite of human antibodies targeting measles virus, revealing new immune response insights and therapeutic potential.
A clinical trial indicates that treating neonatal opioid withdrawal syndrome using symptom-based opioid dosing may shorten hospital stays and reduce medication use compared to…
Two independent teams used advanced genetic and microscopy techniques to uncover a distinct spatial pattern of odor receptors in the mouse nose, enhancing understanding of smell.
A study analyzing pancreatic islet cells from diverse donors reveals variations in hormone-producing cell composition that may influence diabetes risk.
DiscoverWHR provides comprehensive access to NIH-funded women's health research, clinical trials, data elements, literature, patient education, and funding opportunities.
NIH-funded research reveals oral GLP-1 receptor agonists penetrate deep brain regions to suppress pleasure-driven eating and may impact other reward-related disorders.
Research from Cleveland Clinic suggests androgens like testosterone could limit glioblastoma progression by modulating brain immune environment and stress hormones.
Researchers discovered bacteria within both calcium oxalate and struvite kidney stones, suggesting microbes may actively contribute to stone formation beyond infections.
Researchers funded by NIH are investigating ways to improve rehabilitation for stroke survivors to help them regain skills and enhance quality of life.
Burn injuries, often occurring at home, range from mild to severe and require different treatments; new technologies aim to improve healing and treatment accuracy.
Mental health encompasses emotional, psychological, and social well-being. Self-care and timely professional help can support overall health and recovery.
A clinical trial indicates that adding weekly GLP-1 receptor agonist semaglutide to cognitive behavioral therapy may lower heavy drinking days among patients with alcohol use…
Research in mice indicates that alterations in gut microbiomes during aging may weaken gut-brain communication and impair memory, potentially informing future human treatments.
NIH-funded researchers found that blocking fructose metabolism in immune cells called microglia may improve immune activity and survival in mouse models of aggressive brain cancer.
An NIH-funded study developed an AI tool that predicts patients likely to experience intimate partner violence years before help is sought, potentially aiding early intervention.
The National Eye Institute highlights the connection between overall health and vision, promoting regular eye exams and healthy habits for long-term eye care.
An NIH-funded trial suggests that treating neonatal opioid withdrawal syndrome with symptom-based opioid dosing can shorten medication duration and hospital stay.
A machine learning tool analyzes single-cell tumor data to predict survival outcomes and identify high-risk cell populations in melanoma and liver cancer.
Dr. Jonathan M. Green has been named chief executive officer of the NIH Clinical Center, the world’s largest clinical research hospital, effective May 17, 2026.
The Division of Program Integrity at NIH reviews allegations of improper employee conduct, grant misuse, and conflicts of interest related to NIH programs and activities.
The NIH Executive Secretariat represents institutional perspectives, facilitates communication among divisions, and promotes transparency and accountability within NIH.
Developing health communication materials requires understanding the target audience, choosing the right medium, and addressing specific behavioral objectives to enhance message…
The NIH emphasizes clear writing to improve understanding, reduce barriers, and support its mission of making health information accessible to all Americans.
The U.S. Department of Health and Human Services refines health literacy concepts to emphasize informed decision-making and the responsibility of organizations in health…
The NIH Office of the Principal Deputy Director manages daily operations, overseeing research funding, administration, and coordination across NIH Institutes and Centers.
This article provides key contact details for reaching the NIH Office of Communications and Public Liaison, including emails, phone numbers, and mailing address.
The NIH Office of the Director includes several specialized offices providing leadership, support, and resources to fulfill the institute's mission in medical and behavioral…
The NIH pursues groundbreaking initiatives to accelerate scientific discovery and address health needs including genetics, addiction, and disabilities.
NIH job opportunities include unique hiring paths tailored for the general public, veterans, students, and individuals with disabilities, with each position specifying applicable…
The Accelerating Medicines Partnership (AMP) is a public-private collaboration aimed at enhancing diagnostics and therapies while reducing development time and cost.
The NIH HEAL Initiative, launched in 2018, focuses on improving prevention, treatment, and pain management related to opioid misuse and addiction through research.
The NIH released a comprehensive five-year plan to advance research focused on the health and well-being of Americans with disabilities, emphasizing a person-centered approach…
The National Institutes of Health (NIH) is the largest public funder of biomedical and behavioral research, contributing to significant health and scientific progress globally.
The National Institutes of Health invests most of its budget in medical research to improve health outcomes and supports researchers through various funding mechanisms, including…
NIH and associated federal agencies provide detailed instructions for submitting various grant applications, including research, career development, training, and small business…
NIH contracts are legally binding agreements focused on specific deliverables and schedules, differing from grants in oversight, evaluation, and proposal submission processes.
Middle-age weight gain, a natural consequence of aging, involves changes in metabolism and body composition but may be managed through diet and physical activity.
Recent NIH research reveals new insights into brain cell activity in older adults, proteins involved in food allergies, and innovative RNA-based heart attack therapy.
Research indicates that while childhood stress is common, prolonged or traumatic stress may increase risks for chronic health and mental disorders. Supportive relationships may…
Eye discomfort such as tiredness, dryness, and ache can result from prolonged screen use, aging, and environmental factors. Simple steps may help relieve symptoms.
Similar symptoms may make it difficult to tell COVID-19, flu, colds, and allergies apart, but testing can help identify the cause and inform recovery steps.
Developmental Language Disorder (DLD) is a common communication disorder that can persist into adulthood, affecting speech, comprehension, and learning skills in children.
Research indicates that a significant portion of older adults with dementia take medications that affect the brain and nervous system, which may increase risks such as confusion…
Air pollution, both indoors and outdoors, can affect various aspects of health, including respiratory and cardiovascular systems, and may increase the risk of several serious…
A personalized cellular immunotherapy approach may shrink tumors and prevent regrowth in some metastatic colorectal cancer patients, early trial results suggest.
The National Institutes of Health provides free resources including posters and infographics to help increase public understanding and involvement in clinical trials.
This article explains clinical research trials, including terminology, phases, participant types, study designs, and protocols used to test medical treatments.
Clinical trials evaluate new methods to prevent, detect, or treat diseases, offering potential benefits to participants and contributing to medical progress.
Clinical research is medical research that requires consultation with healthcare professionals. Learn how to find trials and get answers to common questions.
An AI algorithm created by NIH may help clinicians efficiently connect potential volunteers with clinical trials, potentially accelerating research progress.
The NIH provides educational materials on clinical research, including types of studies, participant guidance, and special topics like pediatric and Alzheimer’s research.
Clinical trials involve both healthy volunteers and patients, each contributing uniquely to research aimed at advancing medical knowledge and treatments.
The National Institutes of Health maintains searchable databases to help individuals find clinical trials on many diseases and conditions, including rare and chronic illnesses.
Participation in clinical trials plays a crucial role in helping researchers develop better methods to treat, prevent, diagnose, and understand diseases.
The National Institutes of Health highlights the critical role of clinical research in advancing health and the ongoing challenge of recruiting participants for trials.
Several individuals with various medical conditions discuss their experiences participating in NIH clinical trials, highlighting the role of trials in advancing medical…
The National Institutes of Health provides free print wellness toolkits in English and Spanish covering topics like disease prevention, emotional well-being, and environmental…
Clinical research registries collect health information to support research and treatment improvements while maintaining strict privacy protections for participants.
The NIH Office of Communications and Public Liaison (OCPL) manages public, media, and stakeholder communications, coordinating with NIH's Institutes and Centers.
Social connections and caregiving practices can impact mental and physical health. Practical strategies support improved social engagement and caregiver well-being.