Note: Single-source report; awaiting corroboration.

The National Institutes of Health (NIH) provides detailed instructions for grant applications to the NIH, Centers for Disease Control and Prevention (CDC), Food and Drug Administration (FDA), and Agency for Healthcare Research and Quality (AHRQ). These guidelines help applicants prepare proposals according to each agency’s requirements.

Application instructions include standard guidelines for all grants and program-specific call-out boxes tailored to different types, such as research, career development, fellowship, training, multi-project, and small business grants. Applicants should review the instructions for their relevant activity code to ensure compliance.

Instructions are organized by activity codes: Research (R), Career Development (K), Training (T), Fellowship (F), Multi-Project (P), and Small Business Innovation Research/Small Business Technology Transfer (SBIR/STTR). Applicants are guided to select the appropriate set for their specific application type.

Instructions are available in HTML and PDF formats, with updates for submissions due on or after January 25, 2025. The NIH also offers resources on application format, page limits, system issues, and registration to support applicants during submission.